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Andrew Nicolaides scheduled to talk about the ArtAssist® Device at Veith Symposium 2012

We are excited to announce that at this year’s Veith Symposium in New York, Professor Nicolaides will be giving a short presentation about our own ArtAssist® pneumatic compression device.

As one of the ArtAssist® Device’s key developers, Prof. Nicolaides is a veritable expert on the machine’s capability to treat non-surgical patients suffering from severe PAD. If anyone can give a great 5-minute talk about our new technology at 6:46 a.m., it would be him.

Are you attending Veith 2012? Roll out of bed, grab some coffee (or whatever you do to wake up…I don’t judge), get dressed with as much coordination as you can muster, and make your way down to the lecture hall on Friday, November 16 from 6:46 – 6:51 a.m. to listen to “How The Art-Assist Pneumatic Compression Device Can Heal Ulcers From CLI And Relieve Rest Pain Noninvasively.”

As a man of vast knowledge, Prof. Nicolaides will also be presenting on a couple of other topics. Check out his schedule by clicking here.

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Research at the Imperial College of London suggests IPC therapy helps keep arterial bypass grafts in shape

artassist compression sequence device

ArtAssist®…The Arterial Assist Device®

Research carried out at the Imperial College in London shows that an intermittent pneumatic compression (IPC) therapy regimen applied to lower limbs with peripheral arterial disease (PAD) can extend the life and efficacity of infrainguinal arterial bypass grafts. Starting with the knowledge that IPC already dramatically enhances blood flow to the lower extremities, researchers in London tested their hypotheses on patients who had already undergone successful bypass surgery in hopes that IPC therapy would improve the performance of the new vascular system. They were not disappointed.

“IPC was effective in improving infrainguinal graft flow velocity, probably by reducing peripheral resistance,” states the last line of one abstract of a study led by Konstantinos Delis, MD, PhD. “IPC has the potential to reduce the risk of bypass graft thrombosis.”

Many patients with ischemic limbs choose to have a bypass procedure done to restore arterial blood flow to their lower extremities. Though bypass procedures are often a reliable treatment solution for limb ischemia, the newly-revascularized limb is still susceptible to returning to its atherosclerotic state if regular blood flow is not maintained.

To prevent return of this disease’s symptoms, some patients are able to exercise regularly. Others, however, remain in danger of being revisited by PAD’s painful consequences.

This is where IPC therapy comes in:  by sequentially compressing the foot, ankle and calf, IPC mimics the physiological benefits of taking a brisk walk. Both walking and IPC activate the calf muscle pump, which pushes venous blood back towards the heart to be re-oxygenated and sent back to the legs at a greater velocity. This increase in blood flow effectively increases chances of recovery from the effects of PAD.

In one study, researchers at the Imperial College of London applied an IPC device to patients who had already successfully undergone an arterial bypass graft (femoropopliteal & femorodistal). Five outcome measures, including volume flow in the grafts, yielded encouraging results directly after IPC therapy. Blood flow had improved significantly in all areas for both types of bypass grafts.

Having one more option for maintaining healthy blood flow to the lower limbs could dramatically change a PAD patient’s quality of life by decreasing the number of surgical procedures and time spent in the hospital.

The IPC device used in this clinical study was the ArtAssist® Arterial Pump developed by ACI Medical, LLC.

Reference:

Haemodynamic Effect of Intermittent Pneumatic Compression of the Leg After Infainguinal Arterial Bypass Grafting. Delis, K. et al. St. Mary’s Hospital, Imperial College School of Medicine, London, UK. Br J Surg 2004; 91: 429-34

Other studies of interest:

Enhancing Foot Skin Blood Flow in Patients with Infrainguinal Arterial Bypass Grafting Using Intermittent Pneumatic Compression. Husmann, M.J.W.; Delis, K.T.; Lennox, A.F.; Nicolaides, A.N.; Standsby, G. Irvine Laboratory for Cardiovascular Research, St. Mary’s Hospital, London, UK. 21st Conference in Microcirculation, June 2000

Effects of Intermittent Pneumatic Compression of the Calf and Thigh on Arterial Calf Inflow: A Study of Normals, Claudicants, and Grafted Arteriopaths. Delis, K.T.; Husmann, J.W.; Cheshire, N.J.; and Nicolaides, A.N. Imperial College School of Medicine, St. Mary’s Hospital, London, UK. Surgery, 2000, Vol. 129, No. 2, p. 188-195

Enhancing Foot Skin Blood Flux in Peripheral Vascular Disease Using Intermittent Pneumatic Compression: Controlled Study on Claudicants and Grafted Arteriopaths. Delis, K.T.; Husmann, M.J.W.; Nicolaides, A.N.; Wolfe. J.H., and Cheshire, N.J., Imperial College School Of Medicine, St. Mary’s Hospital, London, UK. World Journal Surgery, 2002 Jul;26(7):861-6

Andrew N. Nicolaides on IPC’s potential to enhance endovascular procedures (video)

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Compressing the foot and why it’s so important

Why calf-only arterial pumps are missing out

ArtAssist device compression sequence

ArtAssist®…The Arterial Assist Device® Compression Sequence

Calf-only arterial pumps are missing a key component because foot compression is essential to improving circulation in the skin of the foot. Good circulation is vital to the successful healing wounds and ulcers. ACI Medical’s ArtAssist® device went through numerous clinical trials in order to optimize compression therapy for treating peripheral arterial disease of the legs and feet.

Researchers and engineers optimizing the ArtAssist® device not only discovered the importance of compressing the foot in addition to the calf, but they also designed this arterial pump technology to imitate the physiological act of walking as closely as possible.

A bit of background

An early study to determine the physiological effects of  intermittent pneumatic compression therapy focused compression on the calf, foot, and both simultaneously.

Although significant increase in arterial blood flow was recorded for individual compression areas, the simultaneous combination yielded disappointing results because blood was not flowing back to the heart as anticipated.

After the conclusion was drawn that simultaneous compression did not produce the desired augmented blood flow for all tissues below the knee, researchers realized that the answer lay in a time delay. Strong, encompassing foot and ankle compression that boosts foot skin perfusion would come first, followed then by calf compression to amplify popliteal flow.

That magical formulation

In essence, foot/ankle compression + calf compression with time delay = successful emptying of venous blood, resulting in improved circulation.

The optimization study led by K. T. Delis, et. al. determined that this foot, ankle and calf compression sequence, applying 120-140 mmHg at a frequency of 3-4 impulses per minute, “provided the optimum intermittent pneumatic stimulus.”

The next logical step was a prospective randomized controlled trial to solidify the efficacy claims.

And the rest is history…

One example of such a trial studied not only the effects of the previously mentioned IPC method, but also the long-term effects on treated claudicants. The results indicated that treated claudicants still retained their ABI’s and walking benefits one year after the end of IPC application.

Following the numerous physiological and optimization studies for the ArtAssist® device, research facilities continued to explore the possibilities of arteriogenesis, therapy for patients with intermittent claudication, and limb salvage.

The ArtAssist® device is currently the only IPC device with this thorough progression of clinical studies and randomized controlled trials to support its efficacy.

References

  1. Improving Popliteal Artery Flow with Intermittent Pneumatic Foot and Calf Compression.” Delis, K.; Labropoulos, N.; Nicolaides, A.N.; Stansby, G.; and Lumley, J. Irvine Laboratory for Cardiovascular Investigation and Research, Academic Surgical Unit, Imperial College School of Medicine, St. Mary’s Hospital, London, UK.
  2. Enhancing Venous Outflow in the Lower Limb with Intermittent Pneumatic Compression. A Comparative Haemodynamic Analysis on the Effect of Foot vs. Calf vs. Foot and Calf Compression.” Delis, K.T.; Slimani, G.; Hafez, H.M. and Nicolaides, A.N. Irvine Lab for Cardiovascular Investigation and Research, Academic Vascular Unit, Imperial College School of Medicine, St. Mary’s Hospital, London UK. Eur J Vasc Endovasc Surg 19, 250-260; 2000
  3. The Acute Effects of Intermittent Pneumatic Foot and Calf Compression on Popliteal Artery Hemodynamics: A Comparative Study.” Delis, K.T.; Nicolaides, A.N.; Labropoulos, N.; and Stansby, G. Imperial College School of Medicine, St. Mary’s Hospital, London, UK. J Vasc Surg, 2000; 32: 284-92
  4. Intermittent Calf and Foot Compression Increases Lower Extremity Blood Flow.” Eze, A.R.; Comerota, A.J.; Cisek, P.L.; Holland, B.S.; Kerr, R.P.; Veeramasuneni, R.; Comerota, A.J. Jr. Presented at the 24th Annual meeting of the Society for Clinical Vascular Surgery; March 1996. Am J Surg 1996; 172:130-135
  5. Optimum Intermittent Pneumatic Compression Stimulus for Lower-limb Venous Emptying.” Delis, K.T.; Azizi, A.A.; Stevens, R.J.G.; Wolfe, J.H.N.; Nicolaides, A.N. Eur J Vasc Endovasc Surg 19, 261-269 (2000).
  6. Improvement in Walking Ability, Ankle Pressure Indices and Quality of Life in Vascular Claudication Using Intermittent Pneumatic Foot and Calf Compression; A Prospective Randomized Controlled Trial with 1 Year Follow-up.” Delis, K.T.; Nicolaides, A.N.; Cheshire, N.J.W.; and Wolfe, J.H.N. Academic Vascular Surgery, St. Mary’s Hospital, London, UK. Presented at the Vascular Surgical Society of Great Britain & Ireland, Nov. 2000, London Arena.
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Challenge conventions. You may end up saving a limb!

Previously, I posted a whole article about how it’s actually not dangerous to use compression therapy on an ischemic limb. However, that’s not the only misconception that we’ve cleared up at ACI Medical. This article exposes a couple more myths that have been known to float around, and how we’ve found evidence to set the record straight.

Even after some experts dismissed the idea of intermittent pneumatic compression (IPC) as a viable treatment for patients with PAD, the creators and developers of the ArtAssist® device put their theories to the test nonetheless.

Pioneered and developed with vascular surgeons, the ArtAssist® device continues to be the leader in IPC therapy for non-surgical PAD patients with varying levels of severity.

ArtAssist® IPC therapy should not be overlooked or dismissed without having considered the clinical evidence:

in fact, it has both saved limbs and improved patient quality of life.

MYTH: Critically ischemic limbs are maximally vasodilated.

False.

In fact, the ArtAssist® device’s first physiological clinical trial disproves this myth. Even without having been optimized to the extent it is now, the prototype yielded results that suggested transient vasodilation.

Later, in 2005, a study conducted by Professor Labropoulos of SUNY not only confirms the earlier findings, but also suggests that increasing the arteriovenous pressure gradient with foot & calf IPC therapy contributes greatly to significantly increased blood flow in the subjects’ popliteal, gastrocnemial and collateral arteries. Skin blood flow also improved significantly in their findings.

MYTH: The ArtAssist® device is the same as any other arterial pump with similar function.

False.

We encourage you to ask yourself these two important questions when considering other devices which claim to perform as efficaciously as the ArtAssist® device:

1. Is it optimized for arterial disease? And

2. Is there clinical evidence and support for this specific device?

Only the ArtAssist® device satisfies each of these questions with its thorough progression of clinical studies: this device alone has been adjusted and optimized from its initial prototype over the past two decades to effectively treat even the most severe cases of PAD.

  • Physiological
  • Optimization
  • Intermittent Claudication
  • Limb Salvage
  • Critical Limb Ischemia (CLI)
  • Arteriogenesis (Collateralization)

Currently, studies are being conducted to explore the ArtAssist® device’s efficacy for adjunct therapies, such as stem cell treatment and gene expression.

The Bottom Line.

Your patient’s non-reconstructable limb will not wait for hearsay on this form of therapy.

We are here to let you know that therapy with the ArtAssist® device gives patients a dependable option that continues to help non-surgical limbs across the country.

Make the decision that could save your patient from amputation.

References

Augmentation of blood flow in limbs with occlusive arterial disease by intermittent calf compression. Van Bemmelen, P.S.; Mattos, M.A.; Faught, W.E.; Mansour, M.A.; Barkmeier, L.D.; Hodgson, K.J.; Ramsey, D.E.; and Sumner, D.S. Springfield, IL. Journal of Vascular Surgery 1994; 19:1052-8.

Hemodynamic effects of intermittent pneumatic compression in patients with critical limb ischemia. Labropoulos, N.; Leon, L.R.; Bhatti, A.; Melton, S.; Kang, S.S.; Mansour, A.M.; and Borge, M. The Department of Surgery, Loyola University Medical Center, Maywood, IL. Journal of Vascular Surgery, October 2005; Volume 42, Number 4: 710-716

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Compressing Ischemic Limbs and Why It’s Beneficial

To download a printable PDF of this article, click here:  Compressing Ischemic Limbs and Why It’s Beneficial

The Misconception

Is it true that arterial occlusive disease is an absolute contraindication for intermittent pneumatic compression (IPC)?

The Answer

Not at all!

Unfortunately, many medical professionals are under the impression that applying even a small external pressure to an ischemic limb with reduced distal arterial pressures may serve to reduce or completely stop the already-compromised blood flow. This article presents strong evidence that, contrary to popular belief, IPC can bring life-changing benefits to those who cannot undergo revascularization.

History

Part of the reason this dogma exists is because, for many who consider it, applying IPC to ischemic limbs seems counterintuitive and likely dangerous. Also contributing to this myth are the literature reviews written by investigators as far back as 1934 who showed a poor understanding of the physiological mechanisms. Though these measured acute effects of compression on increased blood flow in ischemic limbs and relief of symptoms, the assessments made about IPC therapy were muddled due to the use of a great variety of compression schemes and devices. This lack of clarity resulted in literature that only served to feed misgivings about IPC as a treatment modality.

Physiological & Optimization Studies | ACI Medicalarteriovenous pressure gradient

To demystify the true value of IPC, our goal was to determine the physiological mechanisms of action, to optimize IPC design for maximal acute effect, and to determine if there is a clinical benefit to patients with lower extremity ischemic disease.

We started with physiological studies1 with compression applied to the dependent limb, which showed these acute mechanisms:

  • Increased arterial-venous pressure gradient
  • Reduced peripheral resistance
  • Abolition of the veno-arteriolar reflex

Further studies2 concerned optimization:

  • Pressure:  at least 120 mmHg
    This high pressure is required to empty the veins in the dependent limb, which temporarily reduces venous pressure to near zero and increases the arterial-to-venous pressure gradient and therefore, flow. Reducing venous pressure also serves to temporarily abolish the veno-arteriolar reflex, which allows for arteriolar dilation.
  • Timing:  3 second pulses followed by 17 seconds of low pressure
    An essential requirement for an arterial pump is the ability to quickly reach inflation and deflation pressures with rise times of 0.25 to 0.30 seconds and fall times under 0.5 seconds.  This rapid squeeze and release creates blood velocities that apply shear stress to the endothelium which releases nitric oxide and further supports the large acute vasodilatory effect in the arterioles.
  • Compressed tissues:  foot, ankle and calf regions
    In order to maximize blood flow through the major arteries and to the toes where ischemic disease often presents, we found that a circumferential foot bladder including the ankle should be compressed first, followed one second later by compression of the calf with a relatively large asymmetrical bladder.

Randomized Controlled Trials | ACI Medical

Intermittent Claudication

Once the arterial IPC device was optimized, three randomized controlled trials3 were performed on patients with intermittent claudication. Not only did these trials yield significantly increased walking distances of two to three times, but also sustained “permanent” improvements begged the question, “What long term mechanisms might be at work?”

Limb Salvage due to Arteriogenesis

Further studies4 showed that arteriogenesis (the opening of collaterals) was responsible for improved ABI’s, PVR’s, toe pressures and popliteal flow. A recently published study from 20105 reported a 94% limb salvage rate at 3.5 years in patients who were unable to undergo revascularization procedures.

Arterial Assist Device, NOT Lymphedema Pump

ArtAssist Arterial Assist Device

ArtAssist®…The Arterial Assist Device®

Today, it is widely-known that IPC devices are designed for prophylaxis against deep vein thrombosis (DVT) and for treatment of lymphedema. However, the understanding behind these devices does not coincide with our exploration of IPC to treat severe forms of arterial disease. Lymphedema and DVT devices do not apply enough pressure to the dependent limb to adequately empty the veins, nor do they apply and release pressure rapidly enough to stimulate release of nitric oxide (NO). While such devices will not significantly improve blood flow in the ischemic limb, it is difficult to say whether they would be harmful without further study.

References in this Publication

  1. Effect of intermittent pneumatic foot compression on popliteal artery haemodynamics. Delis, K.T.; Labropoulos, N.; Nicolaides, A.N.; Glenville, B.; and Stansby, G. Imperial College School of Medicine, Academic Vascular Surgery, St. Mary’s Hospital, London, UK. Eur J Vasc Surg, p. 270-277, vol. 19, no. 3, March 2000.
  2. Optimum intermittent pneumatic compression stimulus for lower-limb venous emptying. Delis, K.T.; Azizi, A.A.; Stevens, R.J.G.; Wolfe, J.H.N. and Nicolaides, A.N. Irvine Lab for Cardiovascular Investigation and Research Academic Vascular Surgery, Imperial College School of Medicine, St. Mary’s Hospital, London, UK. Eur J Vasc Endovasc Surg 19, 261-269 (2000).
  3. Improvement in walking ability, ankle pressure indices and quality of life in vascular claudication using intermittent pneumatic foot and calf compression:  a randomized controlled trial. Delis, K.T.; Nicolaides, A.N.; Cheshire, N.J.W.; Wolfe, J.H.N. St. Mary’s Hospital, London, UK. British Journal of Surgery December 2002; Volume 88, Issue 4:605-606.
  4. Angiographic improvement after rapid intermittent compression treatment (ArtAssist®) for small vessel obstruction. Van Bemmelen, P.; Char, D.; Giron, F.; and Ricotta, J.J. Dept. of Surgery, Div. of Vascular Surgery, State University of New York at Stony Brook, NY. Ann Vasc Surg 2003; 17:224-228.
  5. Sequential compression biomechanical device in patients with critical limb ischemia and nonreconstructable peripheral vascular disease. Sultan, S.; Hamada, N.; Soylu, E.; Fahy, A.; Hynes, N. and Tawfick, W. Department of Vascular and Endovascular Surgery, University College Hospital, Galway, Journal of Vascular Surgery 2011; 54:440-447.
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Building collateral arteries with ArtAssist® device compression therapy

Arteriogenesis:  the key to success

For patients who are surgical candidates, the solution to their arterial obstruction comes as quickly as a surgeon can work.

English: podiatric surgery

English: podiatric surgery (Photo credit: Wikipedia)

However, this means that non-operable patients and their doctors are left to find alternative solutions to improving lower extremity circulation. Drugs and lifestyle changes may work as long as the regimen is maintained, but these may still present problems according to each patient’s case.

Patients who use the ArtAssist® device every day for at least 90 days have developed permanent collateral arteries as a result of therapy.

This solution may be ideal for doctors with patients who have otherwise run out of options. With proven efficacy and consistently high success rates, those with severe PAD get another chance to rebuild and strengthen the collateral arteries in their lower extremities.

The theory

When developers optimized the ArtAssist® device to maximize blood flow to the lower extremities, they realized that, even after having stopped therapy with the device, patients kept their improved circulation. “Why is this?” they asked.

After some educated guessing, Paul van Bemmelen, MD, PhD of Temple University began looking into the hypothesis more closely. This publication (Fig. 1) is the first to have documented a threatened limb before and after four months of ArtAssist® device therapy.

The Rabbit study

In 2007, Dr. van Bemmelen performed another study, this time with a rabbit model. He and his team were able to confirm that intermittent pneumatic compression on the experimental limbs increased the number of angiographical collateral arteries.

How it works

Arteriogenesis, the growth of collateral arteries, can be achieved with a regimen of intermittent pneumatic compression, as we’ve just seen. But what actually happens inside the vessels?

Rapid compression causes shear stress on the endothelial cells. These cells react by releasing nitric oxide (NO), which acts as a vasodilator, and tissue factor pathway inhibitor (TFPI), which acts as an anticoagulant. These two substances ease the path of nutrient-rich blood through the collateral arteries.

Within a month, patients with peripheral arterial disease (PAD) typically begin to see a dramatic increase in arterial blood flow if they use the ArtAssist® device every day.

After about 90 days, the benefits can be visualized in an arteriogram, as seen above. After this point, a patient may be able to discontinue ArtAssist® device therapy.

Obtaining therapy

Both physicians and patients can contact ACI Medical for information and ordering:  toll free (888) 453-4356 or info@acimedical.com

More detailed information can be found at acimedical.com/artassist/order.

References

Angiographic Improvement After Rapid Intermittent Compression Treatment (ArtAssist®) for Small Vessel Obstruction
van Bemmelen, P.; Char, D.; Giron, F; and Ricotta, J.J. Department of Surgery, Division of Vascular Surgery, State University of New York and Stony Brook, NY, USA. Ann Vasc Surg 2003;17:224-228

Long-term Intermittent Compression Increases Arteriographic Collaterals in a Rabbit Model of Femoral Artery Occlusion 
van Bemmelen, P.S.; Choudry, R.G.; Salvatore, M.D.; Goldenberg, B.I.; and Blebea, J. Departments for Surgery, and Pathology, Temple University, Philadelphia, USA.
Eur J Vasc Endovasc Surg 34, 340-346 (2007) 

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Arterial Pump Choosing Guide

At ACI Medical, we know that there are more home-use intermittent pneumatic compression devices (in other words, arterialArtAssist device patient pumps) similar to the ArtAssist® device out on the market, but here is the best we can say for them:  they may work, they may not. This is because the ArtAssist® device is the only device of its kind to have been optimized to treat arterial disease through clinical trials at multiple independent centers. In other words, research done on the ArtAssist® device itself supports our claims about its capabilities.

Through numerous clinical trials, ACI Medical’s researchers have determined what the ArtAssist® device system needs to increase blood flow to the lower extremities as much as it does. If you’re thinking about getting an arterial pump to treat PAD (peripheral arterial disease), here’s what you should look for and why:

Cuff Specifications

Bladder Locations

artassist arterial pump cuff

It is important to have air bladders compressing the foot, ankle and calf regions because this promotes more blood flow to the skin.

When you are considering an arterial pump, also take a look at the size of the air bladders. The larger they are, the more tissue they’re

going to reach. The more tissue they reach, the more circulation.

Inflation and Deflation Rates

Research shows that quick inflation and deflation rates of the air bladders (less than half a second) put what’s called shear stress on your blood cells. Shear stress is good, because when your endothelial cells experience it, they release a muscle relaxant (or a vasodilator called nitric oxide) that helps open the small collateral arteries that are capable of naturally bypassing the blocked artery. It takes around 3 months, and the improvements are long-term. We call this process arteriogenesis or collateralization

Now, this process I described does take a lot longer (typically between 3-6 months) than an open bypass operation, but for people who aren’t good candidates for surgery, it may be worth it to look into arterial pump treatment.

Cuff Pressure

ArtAssist compression sequence 120mmhg

Rapid sequential compression

Now you know that cuffs should have large bladders at the foot, ankle and calf and that they should inflate and deflate quickly. But what kind of pressure should the air bladders reach?

The answer that researchers found was 120 millimeters of Mercury (mmHg), which is about the pressure of a very firm handshake. Below this pressure, blood flow was not as high. Above 120 mmHg was unnecessary and, furthermore, uncomfortable for patients.

Clinical Research

You know I’ve been hinting at it, and I can’t stress it enough:  make sure the device you invest in has clinical research supporting its claims. Research done at respected institutions is usually a very good sign for an arterial pump you’re considering. Also, if you can find a study that’s been done on patients with your diagnosis, even better!

UPDATE:

Being optimized to treat arterial disease is of the utmost importance. Research at the Mayo Clinic suggested that if a pump is NOT optimized for arterial disease, using it could actually DECREASE blood flow – a waste of your precious time and money! For example, some arterial pumps on the market have been modified from DVT prophylaxes and do not have much published clinical support.

So, like any decision you make concerning your health, I encourage you to do a bit of research and ask yourself:  did the makers of this arterial pump design it specifically to treat arterial disease? Straight answers are the best.

Customer Service

Patient Compliance

Basically, make sure you can commit to using your arterial pump for however often your physician has prescribed it. As an example, we’ve seen the ArtAssist® device do amazing things for people – and it’s because they got into the habit of using it every day.

Patient Accommodation

Are you dealing with a special condition? Have you already had a below-knee amputation or are you unable to tolerate foot compression? Is your situation unique? It’s helpful to know that your arterial pump provider is knowledgeable enough to listen to what you’re going through and find a solution so you can get the therapy you need.

Obtaining Your Therapy

Just consider:  how many numbers do you have to call to get an arterial pump? Do you have to go to a clinic every day or can you conveniently keep it at home? Find an arterial pump provider that makes it as easy as possible.

The Arterial Pump That Comes Out On Top

artassist device arterial pump technologyThere’s only one number to call if you want to order, prescribe, or just get more information about the ArtAssist® device:  (888) 4 LEG FLO (888-453-4356). Alternatively, you can email info@acimedical.com any time of the day.

For our references, see our Clinical Studies page.

To read documented success stories of ArtAssist® device patients, take a look through the Case Reports page.

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Also at Desert Foot 2011: Ideal Adjunct Therapy Solutions

In addition to our theme of laser Doppler demonstrations with the ArtAssist® device, we will also be giving out information about how ArtAssist® therapy can be used in conjunction with other treatments.

Take, for example, a case report from Dr. Darwin Eton and Dr. Hong Yu (both from the University of Chicago). They combined intermittent pneumatic compression (IPC) therapy (with the ArtAssist® device) with specific doses of a growth factor called granulocyte-colony stimulation factor (G-CSF…and what a mouthful!).

Though the two patients were of different genders and ages and had different conditions, the combination of IPC and G-CSF worked to heal both of their limbs within a year.

Patient 1’s lower extremity necrosis was healed after 5 months of adjunct therapy and Patient 2’s dorsal ankle ulcer and exposed Achilles’ tendon was healed after one year.

You can read the abstract at this link (CLICK HERE).

And again, if you’re going to Desert Foot next week, we hope to see you there!

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